In addition to l-arginine, ProArgi-9 Plus contains other important ingredients such as citrulline, red wine extract, pomegranate, folic acid, and vitamins B6, B12, K2 and D3. These ingredients enhance the cardiovascular benefits of arginine and also provide a variety of additional health benefits.
Like l-arginine, citrulline is an amino acid important to heart health. Once ingested, citrulline is metabolized in the body where it in turn yields more l-arginine. Research shows that citrulline can help optimize blood flow throughout the body and promote healthy energy levels. Citrulline also plays a role in other processes in the body, including energy production and the prevention of fatigue.
Pomegranate contains superior antioxidants, known as punicalagins and ellagic acid. Pomegranate inhibits LDL oxidation, supports arterial wall strength and enhances the activity of eNOS, the enzyme responsible for converting l-arginine to nitric oxide.
The typical French diet is often high in fat, but the French have a lower incidence of heart disease. This occurrence is often referred to as the French Paradox. The lower rate of heart disease is in part attributed to the frequent consumption of red wines. However, red grapes do not have to be ingested in wine form to reap the health benefits. Red wine extract is high in antioxidants, anthocyanins and phenols, which help protect the heart and reduce LDL oxidation.
Vitamin D3 has long been known to aid in calcium absorption, but new research shows that D3 also plays a role in healthy cardiovascular function. Vitamin D3 can help maintain blood pressure levels within the normal range by inhibiting renin, and enzyme released by the kidneys that acts to affect blood pressure. Vitamin D receptors (VDR) may play a role in regulating blood vessel relaxation. Vitamin D3 activates VDR, which in turn exerts a positive effect on cardiovascular function.